Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16937601 | 1.00 | EPHX1 (0.50) | EPHX1SHBGGAAL3MBTL1CYP2C9 | |
| SCHEMBL172339 | 1.00 | EPHX1 (0.50) | EPHX1SHBGGAAL3MBTL1CYP2C9 | |
| SCHEMBL16937617 | 0.98 | EPHX1 (0.53) | EPHX1SHBGGAAL3MBTL1CYP2C9 | |
| SCHEMBL1149128 | 0.98 | EPHX1 (0.53) | EPHX1SHBGGAAL3MBTL1CYP2C9 | |
| SCHEMBL14605831 | 0.98 | EPHX1 (0.53) | EPHX1SHBGGAAL3MBTL1CYP2C9 | |
| SCHEMBL17821888 | 0.98 | EPHX1 (0.48) | EPHX1SHBGGAAL3MBTL1CYP2C9 | |
| SCHEMBL7775285 | 0.98 | EPHX1 (0.53) | EPHX1SHBGGAAL3MBTL1CYP2C9 | |
| SCHEMBL172679 | 0.98 | EPHX1 (0.53) | EPHX1SHBGGAAL3MBTL1CYP2C9 | |
| SCHEMBL17041918 | 0.95 | EPHX1 (0.47) | EPHX1SHBGGAAL3MBTL1CYP2C9 | |
| SCHEMBL17821880 | 0.95 | EPHX1 (0.52) | EPHX1SHBGGAAL3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230051404-A1 | IMMUNOGENIC COMPOSITIONS COMPRISING NUCLEIC ACIDS FOR RAS PEPTIDES | Think Therapeutics, Inc. | 2023-02-16 | — | — | US | disclosed |
| US-20220160848-A1 | IMMUNOGENIC COMPOSITIONS COMPRISING NUCLEIC ACIDS FOR RAS PEPTIDES | Think Therapeutics, Inc. | 2022-05-26 | — | — | US | disclosed |
| US-11235039-B1 | Immunogenic compositions comprising nucleic acids for RAS peptides | Think Therapeutics, Inc. (US) | 2022-02-01 | — | — | US | disclosed |
| US-11058751-B1 | Compositions for optimized RAS peptide vaccines | Think Therapeutics, Inc. (US) | 2021-07-13 | — | — | US | disclosed |
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |