Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 16/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14736565 | 0.90 | PDE10A (0.60) | PDE10A | |
| SCHEMBL14736561 | 0.83 | PDE10A (0.51) | PDE10APRMT5WDR77 | |
| SCHEMBL14554710 | 0.80 | PDE10A (0.53) | PDE10APRMT5WDR77 | |
| SCHEMBL14736400 | 0.80 | PDE10A (0.60) | PDE10A | |
| SCHEMBL14736471 | 0.78 | PDE10A (0.78) | PDE10A | |
| SCHEMBL14736399 | 0.78 | PDE10A (0.78) | PDE10A | |
| SCHEMBL14736588 | 0.78 | PDE10A (0.78) | PDE10APRMT5WDR77 | |
| SCHEMBL370295 | 0.78 | PDE10A (0.57) | PDE10A | |
| SCHEMBL12362482 | 0.76 | PDE10A (0.58) | PDE10A | |
| SCHEMBL14736793 | 0.76 | PDE10A (0.61) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015172196-A1 | HETEROCYCLIC COMPOUNDS AND USE OF SAME | MONASH UNIVERSITY (AU) | 2015-11-19 | — | — | WO | disclosed |