Ethylene Glycol

Ethylene Glycol

SCHEMBL17274288

Cc1ccc(C(=O)O)o1.Cc1ccc(C(=O)O)o1.OCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
POLB P06746 4/20 0.53
HPGD P15428 5/20 0.50
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
HSD17B10 Q99714 1/20 0.49
KLK7 P49862 1/20 0.48
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
APOBEC3A P31941 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL17274295 1.00 TDP1 (0.53) TDP1POLBHPGDTSHRSMN1; SMN2
SCHEMBL143244 0.91
Hydrochloric Acid SCHEMBL3047201 0.89 KLK7 (0.53) TDP1POLBHPGDTSHRSMN1; SMN2
SCHEMBL28967674 0.89 KLK7 (0.53) TDP1POLBHPGDTSHRSMN1; SMN2
Di(Hydroxyethyl)Ether SCHEMBL17274270 0.87 POLB (0.46) TDP1POLBHPGDTSHRSMN1; SMN2
Triethylene Glycol SCHEMBL17274255 0.86 POLB (0.45) TDP1POLBHPGDTSHRSMN1; SMN2
Triethylene Glycol SCHEMBL17274341 0.86 POLB (0.45) TDP1POLBHPGDTSHRSMN1; SMN2
Propylene Glycol SCHEMBL17274252 0.85 POLB (0.47) TDP1POLBHPGDTSHRSMN1; SMN2
Propylene Glycol SCHEMBL17274260 0.85 POLB (0.47) TDP1POLBHPGDTSHRSMN1; SMN2
Ethylene Glycol SCHEMBL20377334 0.84 TDP1 (0.64) TDP1POLBHPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015179088-A1 CONVERSION OF 5-(HALOMETHYL)-2-FURALDEHYDE INTO POLYESTERS OF 5-METHYL-2FUROIC ACID XF TECHNOLOGIES INC. (US) 2015-11-26 WO disclosed