SCHEMBL1727708

SCHEMBL1727708

C[CH]C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245656 0.72
Propene SCHEMBL28257920 0.72
SCHEMBL245655 0.72
SCHEMBL1679826 0.72
Acetaldehyde SCHEMBL27493145 0.70
Propene SCHEMBL27748846 0.70
Dichloropropene SCHEMBL4300268 0.70
Hypochlorous Acid SCHEMBL28410055 0.68
SCHEMBL10515074 0.67
SCHEMBL5117779 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751796-A4 CATHETER SYSTEM FOR CONTROLLABLY RELEASING A THERAPEUTIC AGENT AT A REMOTE TISSUE SITE LINDALL ARNOLD W (US) 1998-12-09 EP claimed
EP-0751796-A1 CATHETER SYSTEM FOR CONTROLLABLY RELEASING A THERAPEUTIC AGENT AT A REMOTE TISSUE SITE Lindall, Arnold W. (US) 1997-01-08 EP claimed
US-5470307-A IN RESPONSE TO LIGHT ENERGY LINDALL ARNOLD W (US) 1995-11-28 US claimed
WO-1995024939-A1 CATHETER SYSTEM FOR CONTROLLABLY RELEASING A THERAPEUTIC AGENT AT A REMOTE TISSUE SITE LINDALL ARNOLD W (US) 1995-09-21 WO claimed
EP-0102510-B1 SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONES BASF Aktiengesellschaft (DE) 1987-10-07 EP claimed
US-8921124-B2 Pyrazole-based cyanine dye WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2014-12-30 US disclosed
WO-2012033298-A3 METHOD FOR MANUFACTURING A NOX GAS SENSOR, AND NOX GAS SENSOR MANUFACTURED USING SAME 일진머티리얼즈 주식회사 (KR) 2012-05-10 WO disclosed
CN-102391255-A Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists MERCK SHARP & DOHME 2012-03-28 CN disclosed
EP-2006289-B1 PYRAZOLE-TYPE CYANINE DYE WAKO PURE CHEM IND LTD (JP) 2011-11-30 EP disclosed
CN-102056917-A Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists MERCK & CO INC 2011-05-11 CN disclosed
CN-101910158-A Pyridine and pyrazine derivatives useful in the treatment of cell proliferative disorders ASTRAZENECA AB 2010-12-08 CN disclosed
US-20090069546-A1 PYRAZOLE-BASED CYANINE DYE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-12 US disclosed
EP-2006289-A1 PYRAZOLE-TYPE CYANINE DYE Wako Pure Chemical Industries, Ltd. (JP) 2008-12-24 EP disclosed
CN-100439392-C Novel method for the synthesis of perinidopril and the pharmaceutically acceptable salts thereof SERVIER LAB (FR) 2008-12-03 CN disclosed
CN-100404548-C Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof SERVIER LAB (FR) 2008-07-23 CN disclosed
CN-1286835-C Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents PHARMACIA ITALIA SPA (IT) 2006-11-29 CN disclosed
CN-1826351-A Novel method for the synthesis of perinidopril and the pharmaceutically acceptable salts thereof SERVIER LAB (FR) 2006-08-30 CN disclosed
CN-1826352-A Novel method for the synthesis of perindopril and its pharmaceutically acceptable salts SERVIER LAB (FR) 2006-08-30 CN disclosed
CN-1531535-A Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents 2004-09-22 CN disclosed