SCHEMBL17278043

SCHEMBL17278043

CCCCOCC(CO)CO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.55
TSHR P16473 1/20 0.52
CYP3A4 P08684 1/20 0.47
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 2/20 0.44
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
SPHK1 Q9NYA1 1/20 0.40
HSD17B10 Q99714 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP14 P50281 1/20 0.39
PLA2G2C Q5R387 1/20 0.38
LPAR5 Q9H1C0 4/20 0.38
LPAR1 Q92633 4/20 0.38
LPAR2 Q9HBW0 4/20 0.38
LPAR3 Q9UBY5 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21046008 0.91 USP2 (0.68) USP2LMNAHTTMEN1THRB
SCHEMBL14471352 0.91 USP2 (0.52) USP2TSHRCYP3A4ALDH1A1LMNA
SCHEMBL21046022 0.91 USP2 (0.68) USP2LMNAHTTMEN1THRB
SCHEMBL21046018 0.91 USP2 (0.68) USP2LMNAHTTMEN1THRB
SCHEMBL21046030 0.91 USP2 (0.68) USP2LMNAHTTMEN1THRB
SCHEMBL21046013 0.91 USP2 (0.68) USP2LMNAHTTMEN1THRB
SCHEMBL21046040 0.91 USP2 (0.68) USP2LMNAHTTMEN1THRB
SCHEMBL16367888 0.91 USP2 (0.68) USP2LMNAHTTMEN1THRB
SCHEMBL20898182 0.88 USP2 (0.64) USP2TSHRCYP3A4LMNAHTT
SCHEMBL20898306 0.86 USP2 (0.68) USP2LMNAHTTMEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016050210-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR 厦门赛诺邦格生物科技有限公司 2016-04-07 WO disclosed
WO-2016050209-A1 HETEROFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD, AND BIO-RELATED SUBSTANCE 厦门赛诺邦格生物科技有限公司 2016-04-07 WO disclosed
EP-2947111-A1 MONOFUNCTIONAL BRANCHED POLYETHYLENEGLYCOL AND BIO-RELATED SUBSTANCE MODIFIED BY SAME Xiamen Sinopeg Biotech Co., Ltd. (CN) 2015-11-25 EP disclosed