⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL20358416 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL20358302 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL10616917 | 0.94 | — | — | |
| SCHEMBL1183503 | 0.94 | — | — | |
| SCHEMBL83931 | 0.94 | — | — | |
| SCHEMBL8973957 | 0.88 | — | — | |
| Methylamine SCHEMBL9015777 | 0.78 | — | — | |
| SCHEMBL9160433 | 0.78 | — | — | |
| Bicarbonate SCHEMBL14696469 | 0.72 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL11132176 | 0.72 | CA1 (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319613-A1 | USE OF AMINE CARBOXYBORANES AS THERAPEUTIC DELIVERY OF CARBON MONOXIDE AND AS GENERAL DRUG DELIVERY SYSTEM IN THE PRESENCE OF REACTIVE OXYGEN SPECIES | The Research Foundation for The State University of New York (US) | 2018-05-16 | — | — | EP | claimed |
| WO-2017007955-A1 | USE OF AMINE CARBOXYBORANES AS THERAPEUTIC DELIVERY OF CARBON MONOXIDE AND AS GENERAL DRUG DELIVERY SYSTEM IN THE PRESENCE OF REACTIVE OXYGEN SPECIES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-01-12 | — | — | WO | claimed |
| EP-1218385-A1 | CARBON MONOXIDE SOURCE FOR PREPARATION OF TRANSITION-METAL-CARBONYL-COMPLEXES | Mallinckrodt Inc. (US) | 2002-07-03 | — | — | EP | claimed |
| WO-2001025243-A1 | CARBON MONOXIDE SOURCE FOR PREPARATION OF TRANSITION-METAL-CARBONYL-COMPLEXES | MALLINCKRODT INC. (US) | 2001-04-12 | — | — | WO | claimed |
| EP-0402160-B1 | Amine-Alkylborane derivatives and methods | BORON BIOLOG INC (US) | 1997-03-12 | — | — | EP | claimed |
| EP-0746324-A1 | METHOD OF COMBATTING OSTEOPOROSIS AND OTHER DISEASE STATES IN MAMMALIAN SUBJECTS, UTILIZING ORGANIC BORON COMPOUNDS | BORON BIOLOGICALS, INC. (US) | 1996-12-11 | — | — | EP | claimed |
| EP-0336772-B1 | Boron dipeptide compounds, preparative methods and pharmaceutical applications | UNIV DUKE (US) | 1994-08-10 | — | — | EP | claimed |
| US-5312816-A | Method of combatting osteoporosis in mammalian subjects, utilizing organic boron compounds | BORON BIOLOGICALS, INC. (US) | 1994-05-17 | — | — | US | claimed |
| WO-1993009123-A1 | HETEROCYCLIC AMINO-BORANES | BORON BIOLOGICALS, INC. (US) | 1993-05-13 | — | — | WO | claimed |
| WO-1993005795-A1 | METHOD OF COMBATTING OSTEOPOROSIS AND OTHER DISEASE STATES IN MAMMALIAN SUBJECTS, UTILIZING ORGANIC BORON COMPOUNDS | BORON BIOLOGICALS, INC. (US) | 1993-04-01 | — | — | WO | claimed |
| US-5023513-A | Amine-alkylborane derivatives and methods | BORON BIOLOGICALS, INC. (US) | 1991-06-11 | — | — | US | claimed |
| EP-0402160-A2 | Amine-Alkylborane derivatives and methods | BORON BIOLOGICALS, INC. (US) | 1990-12-12 | — | — | EP | claimed |
| EP-0336772-A2 | Boron dipeptide compounds, preparative methods and pharmaceutical applications | DUKE UNIVERSITY (US) | 1989-10-11 | — | — | EP | claimed |
| EP-0181721-B1 | ESTERS OF BORON ANALOGUES OF AMINO ACIDS | DUKE UNIVERSITY (US) | 1989-08-02 | — | — | EP | claimed |
| US-4647555-A | ANTICHOLESTEROL AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1987-03-03 | — | — | US | claimed |
| EP-0181721-A1 | Esters of boron analogues of amino acids | DUKE UNIVERSITY (US) | 1986-05-21 | — | — | EP | claimed |
| EP-0034238-B1 | PHARMACOLOGICALLY ACTIVE AMINE-CARBOXYBORANES | Duke University (US) | 1985-04-17 | — | — | EP | claimed |
| EP-0034238-A1 | Pharmacologically active amine-carboxyboranes | Duke University (US) | 1981-08-26 | — | — | EP | claimed |
| EP-3319613-B1 | USE OF AMINE CARBOXYBORANES AS THERAPEUTIC DELIVERY OF CARBON MONOXIDE AND AS GENERAL DRUG DELIVERY SYSTEM IN THE PRESENCE OF REACTIVE OXYGEN SPECIES | UNIV NEW YORK STATE RES FOUND (US) | 2023-02-22 | — | — | EP | disclosed |
| EP-0034238-A1 | Pharmacologically active amine-carboxyboranes | Duke University (US) | 1981-08-26 | — | — | EP | disclosed |