Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 1.00 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 1.00 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792794 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL1793921 | 1.00 | — | — | |
| SCHEMBL28171174 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL2926039 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL172772 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL1794389 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL3386370 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL3660713 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL2698594 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL8752676 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099240-A1 | PYRIMIDONE DERIVATIVES CONTAINING TWO FUSED BICYCLIC RINGS | BASF SE (DE) | 2021-05-27 | — | — | WO | disclosed |
| EP-1663994-B1 | TETRAHYDROQUINAZOLINE COMPOUNDS AS INHIBITORS OF VOLTAGE-GATED ION CHANNELS | VERTEX PHARMA (US) | 2012-03-07 | — | — | EP | disclosed |
| EP-0496555-B1 | Corrosion-inhibiting coating compositions | CIBA GEIGY AG (CH) | 1997-11-19 | — | — | EP | disclosed |
| EP-0554023-B1 | Corrosion inhibitors | CIBA GEIGY AG (CH) | 1997-04-23 | — | — | EP | disclosed |
| US-5277709-A | Film forming binder and corrosion inhibitor | CIBA-GEIGY CORPORATION (US) | 1994-01-11 | — | — | US | disclosed |
| US-5250325-A | Corrosion inhibitors | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0554023-A1 | Corrosion inhibitors | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | disclosed |
| EP-0496555-A2 | Corrosion-inhibiting coating compositions | CIBA-GEIGY AG (CH) | 1992-07-29 | — | — | EP | disclosed |