SCHEMBL17280810

SCHEMBL17280810

COc1cc2c(cc1I)oc1ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.59
MEN1 O00255 9/20 0.59
NPC1 O15118 2/20 0.59
POLB P06746 2/20 0.53
MAPT P10636 13/20 0.51
KDM4E B2RXH2 10/20 0.51
HPGD P15428 9/20 0.51
ALDH1A1 P00352 9/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
CYP2D6 P10635 1/20 0.51
HTT P42858 1/20 0.51
GAA P10253 4/20 0.50
RAB9A P51151 2/20 0.49
ALOX15 P16050 1/20 0.49
HSD17B10 Q99714 1/20 0.49
LMNA P02545 4/20 0.48
NPSR1 Q6W5P4 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32663521 1.00 KMT2A (0.59) KMT2AMEN1NPC1POLBMAPT
SCHEMBL8798023 0.81 KMT2A (0.61) KMT2AMEN1NPC1POLBMAPT
SCHEMBL31690261 0.80 AHR (0.66) KMT2AMEN1NPC1POLBMAPT
SCHEMBL22139799 0.80 KMT2A (0.59) KMT2AMEN1NPC1POLBMAPT
SCHEMBL31037267 0.80 KMT2A (0.59) KMT2AMEN1NPC1POLBMAPT
SCHEMBL92042 0.80 KMT2A (0.59) KMT2AMEN1NPC1POLBMAPT
SCHEMBL31690264 0.80 KMT2A (0.59) KMT2AMEN1NPC1POLBMAPT
SCHEMBL12203168 0.79 KMT2A (0.58) KMT2AMEN1NPC1POLBMAPT
SCHEMBL21816786 0.78 KMT2A (0.56) KMT2AMEN1NPC1POLBMAPT
SCHEMBL11766955 0.78 MEN1 (0.60) KMT2AMEN1NPC1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732069-B2 Carbazole compound and organic light emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-15 US disclosed
US-9732069-B2 Carbazole compound and organic light emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-15 US disclosed
US-20150336937-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-11-26 US disclosed
US-20150336937-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336937-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCUDING THE SAME CYP1B1, CCNT1, CHRM1 KMT2A 2872/4885MEN1 811/4885NPC1 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.