Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24680359 | 1.00 | MEN1 (0.32) | MEN1KMT2ATSHRSLC6A2SLC6A4 | |
| SCHEMBL18994380 | 0.98 | KDM1A (0.30) | — | |
| SCHEMBL24680303 | 0.82 | KDM4E (0.34) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19591969 | 0.82 | KDM4E (0.32) | — | |
| SCHEMBL24680341 | 0.82 | — | — | |
| SCHEMBL24680296 | 0.82 | SLC6A2 (0.33) | SLC6A2SLC6A4 | |
| SCHEMBL16997008 | 0.80 | DAO (0.31) | — | |
| SCHEMBL29296429 | 0.80 | TSHR (0.33) | MEN1KMT2ATSHR | |
| SCHEMBL24146795 | 0.80 | KDM4E (0.38) | MEN1KMT2ATSHRSLC6A2SLC6A4 | |
| SCHEMBL24680351 | 0.80 | GAA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768966-B1 | COUMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | INFINITY DISCOVERY INC (US) | 2012-03-07 | — | — | EP | disclosed |