Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138393 | 0.81 | — | — | |
| SCHEMBL10516603 | 0.80 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22878351 | 0.78 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4698946 | 0.78 | — | — | |
| SCHEMBL12618705 | 0.77 | KDM4E (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12312651 | 0.75 | GRIN2D (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13300925 | 0.75 | CYP2D6 (0.35) | — | |
| SCHEMBL20083998 | 0.75 | PIK3CA (0.33) | SLC6A4SLC6A3 | |
| SCHEMBL23011189 | 0.74 | KDM4E (0.45) | SLC6A4SLC6A3 | |
| SCHEMBL17888369 | 0.74 | NPSR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015177326-A1 | 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS WHICH ARE JAK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-11-26 | — | — | WO | disclosed |