Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257688 | 0.91 | MAPK14 (0.84) | MAPK14HPGDHTTLMNACYP3A4 | |
| SCHEMBL2851912 | 0.86 | MAPK14 (0.64) | MAPK14HPGDHTTLMNACYP3A4 | |
| SCHEMBL27593863 | 0.86 | HPGD (0.61) | MAPK14HPGDHTTLMNACYP3A4 | |
| SCHEMBL1680843 | 0.84 | NPC1 (0.71) | MAPK14HPGDHTTLMNACYP3A4 | |
| SCHEMBL5709300 | 0.84 | HPGD (0.84) | MAPK14HPGDHTTLMNACYP3A4 | |
| SCHEMBL13192876 | 0.83 | HPGD (0.62) | MAPK14HPGDHTTLMNACYP3A4 | |
| SCHEMBL13192880 | 0.83 | RNF4 (0.62) | MAPK14HPGDHTTLMNACYP3A4 | |
| SCHEMBL10133183 | 0.83 | NPC1 (0.75) | MAPK14HPGDLMNATSHRKMT2A | |
| SCHEMBL14944099 | 0.83 | MAPK14 (0.61) | MAPK14HPGDHTTLMNACYP3A4 | |
| SCHEMBL6178139 | 0.82 | CYP1A2 (0.51) | MAPK14HPGDHTTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673337-B1 | Arylalkylcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI SA (FR) | 2011-11-23 | — | — | EP | disclosed |
| EP-1972616-A1 | Derivatives of arylalkylcarbamates, process for their preparation and therapeutic application thereof | Sanofi-Aventis (FR) | 2008-09-24 | — | — | EP | disclosed |
| EP-1673337-A2 | ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005033066-A2 | ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2005-04-14 | — | — | WO | disclosed |