Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.70 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.70 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.54 |
| ▸ | HTR3B | O95264 | 5/20 | 0.54 |
| ▸ | HTR3A | P46098 | 5/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858082 | 0.89 | QPCT (0.75) | QPCTQPCTLEPHX1CYP3A4CYP2D6 | |
| SCHEMBL17285591 | 0.88 | QPCT (0.70) | QPCTQPCTLEPHX1CYP3A4CYP2D6 | |
| SCHEMBL9058710 | 0.86 | CYP3A4 (0.68) | QPCTQPCTLCYP3A4CYP2D6TSHR | |
| SCHEMBL17285642 | 0.86 | QPCT (0.67) | QPCTQPCTLEPHX1CYP3A4CYP2D6 | |
| SCHEMBL8396139 | 0.85 | QPCT (0.69) | QPCTQPCTLEPHX1CYP3A4CYP2D6 | |
| SCHEMBL12999042 | 0.83 | QPCT (1.00) | QPCTQPCTLEPHX1CYP3A4CYP2D6 | |
| SCHEMBL8070335 | 0.81 | QPCT (0.64) | QPCTQPCTLEPHX1CYP3A4CYP2D6 | |
| SCHEMBL17483161 | 0.79 | QPCT (0.75) | QPCTQPCTLEPHX1CYP3A4CYP2D6 | |
| SCHEMBL31483846 | 0.78 | QPCT (0.83) | QPCTQPCTLEPHX1CYP3A4CYP2D6 | |
| SCHEMBL17481127 | 0.78 | CYP3A4 (0.74) | QPCTQPCTLEPHX1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147279-A1 | CAROTENOID DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICALLY ACCEPTABLE ESTER OR AMIDE THEREOF | Fuji Chemical Industry Co., Ltd. (JP) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015178404-A1 | CAROTENOID DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICALLY ACCEPTABLE ESTER OR AMIDE THEREOF | 富士化学工業株式会社 | 2015-11-26 | — | — | WO | disclosed |