SCHEMBL172871

SCHEMBL172871

Oc1cc2ccccc2cc1-c1nc2ccccc2n1-c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.59
ESR2 Q92731 5/20 0.56
ESR1 P03372 4/20 0.56
MAPK1 P28482 2/20 0.53
HTT P42858 1/20 0.53
PRKACA P17612 1/20 0.48
RPS6KB1 P23443 1/20 0.48
GSK3B P49841 1/20 0.48
ROCK1 Q13464 1/20 0.48
GRIA1 P42261 1/20 0.48
CACNG8 Q8WXS5 1/20 0.48
CACNG2 Q9Y698 1/20 0.48
RAB9A P51151 1/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
GSR P00390 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4303255 0.84 RECQL (0.67) RECQLESR2ESR1MAPK1HTT
SCHEMBL27889547 0.83 RECQL (0.65) RECQLESR2ESR1MAPK1HTT
SCHEMBL17385550 0.83 RECQL (0.65) RECQLESR2ESR1MAPK1HTT
SCHEMBL13085156 0.82 RECQL (0.71) RECQLESR2ESR1MAPK1HTT
SCHEMBL16692170 0.82 ESR1 (0.60) RECQLESR2ESR1MAPK1HTT
SCHEMBL27702413 0.82 RECQL (0.63) RECQLESR2ESR1MAPK1HTT
SCHEMBL17817813 0.81 RECQL (0.56) RECQLESR2ESR1MAPK1HTT
SCHEMBL18819265 0.81 ESR2 (0.52) RECQLESR2ESR1MAPK1HTT
SCHEMBL4387592 0.81 RECQL (0.55) RECQLESR2ESR1MAPK1HTT
SCHEMBL12854005 0.80 RECQL (0.69) RECQLESR2ESR1MAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521125-B1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH CO LTD (JP) 2012-03-07 EP disclosed
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 US disclosed
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed