SCHEMBL172875

SCHEMBL172875

Cc1ccc(Nc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 1.00
ALDH1A1 P00352 5/20 0.72
HSD17B10 Q99714 4/20 0.72
ALOX12 P18054 4/20 0.72
L3MBTL1 Q9Y468 4/20 0.72
TDP1 Q9NUW8 3/20 0.72
TSHR P16473 3/20 0.72
ALOX15 P16050 2/20 0.72
PTGS1 P23219 1/20 0.72
SLC6A2 P23975 1/20 0.72
MAPK1 P28482 1/20 0.72
PTGS2 P35354 1/20 0.72
HTR2B P41595 1/20 0.72
NPSR1 Q6W5P4 1/20 0.62
GAA P10253 3/20 0.62
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
MAPT P10636 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24137168 1.00 HPGD (1.00) HPGDALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL9461706 1.00 HPGD (1.00) HPGDALDH1A1HSD17B10ALOX12L3MBTL1
Diphenylamine SCHEMBL9215415 0.97 HPGD (0.94) HPGDALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL12958033 0.93 HPGD (0.86) HPGDALDH1A1HSD17B10ALOX12L3MBTL1
Diphenylamine SCHEMBL23466803 0.92 HPGD (0.84) HPGDALDH1A1HSD17B10ALOX12L3MBTL1
Diphenylamine SCHEMBL9215749 0.90 HPGD (0.81) HPGDALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL50079 0.88 HPGD (0.78) HPGDALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL9516537 0.88 HPGD (0.78) HPGDALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL108881 0.88 HPGD (0.78) HPGDALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL401617 0.87 HPGD (0.77) HPGDALDH1A1HSD17B10ALOX12L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3635 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146056-A1 MORPHOLINE-BASED ORGANOPHOSPHINE LIGAND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Henan Academy of Sciences Institute of Chemistry Co., Ltd (CN) 2026-05-28 US claimed
CN-224271192-U Reaction kettle for preparing chemical product 4-methyl diphenylamine Pingdingshan Longwei Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12590249-B2 Etchant composition SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-03-31 US claimed
CN-119912758-A Carbon black composite polystyrene material and preparation method thereof 河北信泰新材料有限公司 2025-05-02 CN claimed
CN-119751506-A Morphinan organic phosphine ligand and preparation method and application thereof 河南省科学院化学研究所有限公司 2025-04-04 CN claimed
CN-119390586-A Process for preparing aromatic polyamine mixtures 巴斯夫欧洲公司 2025-02-07 CN claimed
CN-116920634-B Hydrophilic modification method of polytetrafluoroethylene microporous membrane 广东宏瑞能源科技股份有限公司 2024-06-28 CN claimed
CN-118022568-A Modified polytetrafluoroethylene film for adsorbing metal ions and preparation method and application thereof 广东宏瑞能源科技股份有限公司 2024-05-14 CN claimed
CN-114671888-B Organic compound, organic light-emitting element, display device, photoelectric conversion device, electronic device, illumination device, and exposure light source 佳能株式会社 2024-05-03 CN claimed
CN-116920634-A Hydrophilic modification method of polytetrafluoroethylene microporous membrane 广东宏瑞能源科技股份有限公司 2023-10-24 CN claimed
EP-0691997-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1996-01-17 EP claimed
WO-1994021722-A1 STABILIZED POLYETHER POLYOL AND POLYURETHANE FOAM OBTAINED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-09-29 WO claimed
US-5338478-A Mixture of diarylamine, hindered phenol and pentaerythritol diphosphite as stabilizer for polyether intermediate for polyetherurethane copolymer UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-08-16 US claimed
EP-0606858-A1 Liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 1994-07-20 EP claimed
US-5256333-A Diarylamine, hindered phenol and a pentaerythritol diphosphite UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-26 US claimed
WO-1993011114-A1 AMINE ANTIDEGRADANTS FOR UNSATURATED POLYMERS UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-10 WO claimed
US-5147621-A Amine stabilizer CHEMIE AG BITTERFELD-WOLFEN (DE) 1992-09-15 US claimed
EP-0432199-A1 COMPOSITION FOR THE TREATMENT OF ERECTILE DYSFUNCTION. AMSU LTD (GB) 1991-06-19 EP claimed
WO-1990002545-A1 COMPOSITION FOR THE TREATMENT OF ERECTILE DYSFUNCTION AMSU, LTD. (GB) 1990-03-22 WO claimed
EP-0357581-A1 Composition for the treatment of erectile dysfunction AMSU, Ltd. (GB) 1990-03-07 EP claimed