Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237415 | 1.00 | SCN10A (0.54) | SCN10ANPC1RAB9APARP1KDM4E | |
| SCHEMBL240426 | 0.90 | SCN10A (0.53) | SCN10APARP1 | |
| SCHEMBL240073 | 0.90 | SCN10A (0.47) | SCN10A | |
| SCHEMBL12727049 | 0.90 | SCN10A (0.55) | SCN10APARP1 | |
| SCHEMBL2756363 | 0.90 | SCN10A (0.55) | SCN10APARP1 | |
| SCHEMBL237254 | 0.90 | SCN10A (0.55) | SCN10APARP1 | |
| SCHEMBL242682 | 0.88 | SCN10A (0.51) | SCN10APARP1 | |
| SCHEMBL240766 | 0.87 | SCN10A (0.71) | SCN10ANPC1RAB9AMAPT | |
| SCHEMBL238305 | 0.87 | SCN10A (0.50) | SCN10APARP1 | |
| SCHEMBL238084 | 0.86 | SCN10A (0.49) | SCN10ANPC1RAB9APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2692346-B1 | An antiviral 1-phenyl-2,5-dibenzimidazol-5-yl-pyrrolidine derivative | ABBVIE BAHAMAS LTD (BS) | 2015-12-02 | — | — | EP | disclosed |