Propyl Gallate

Propyl Gallate

SCHEMBL1728841

CCCOC(=O)c1cc(O)c(O)c(O)c1.OCC(O)CS

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.58
AKR1C4 P17516 1/20 0.56
AKR1C3 P42330 1/20 0.56
AKR1C2 P52895 1/20 0.56
AKR1C1 Q04828 1/20 0.56
SERPINE1 P05121 5/20 0.55
TYR P14679 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 1/20 0.44
CHRM1 P11229 1/20 0.44
TSHR P16473 1/20 0.44
SLC6A2 P23975 1/20 0.44
KDR P35968 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propyl Gallate SCHEMBL3147225 0.92 ESR1 (0.65) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL1429770 0.86 ESR1 (0.65) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL6427209 0.84 ESR1 (0.75) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL22630 0.84 ESR1 (0.80) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL788397 0.84 ESR1 (0.80) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL16585562 0.83 ESR1 (0.61) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL16678445 0.82 ESR1 (0.77) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL29910229 0.82 ESR1 (0.77) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL9389174 0.82 ESR1 (0.77) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
Propyl Gallate SCHEMBL8334443 0.82 ESR1 (0.77) ESR1AKR1C4AKR1C3AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501496-B1 FORMULATIONS CONTAINING AMIODARONE AND SULFOALKYL ETHER CYCLODEXTRIN CYDEX PHARMACEUTICALS INC (US) 2011-11-30 EP disclosed
US-5664704-A Dropwise liquid dispensing system particularly suitable for liquids having low surface tension ALLERGAN, INC. (US) 1997-09-09 US disclosed
EP-0758997-A1 DROPWISE LIQUID DISPENSING SYSTEM PARTICULARLY SUITABLE FOR LIQUIDS HAVING LOW SURFACE TENSION Allergan (US) 1997-02-26 EP disclosed
US-5564596-A Multiple fluid dispensing device for low surface tension formulations ALLERGAN, INC. (US) 1996-10-15 US disclosed
US-5497910-A Dropwise liquid dispensing system particularly suitable for liquids having low surface tension ALLERGAN, INC. (US) 1996-03-12 US disclosed
WO-1995030606-A1 DROPWISE LIQUID DISPENSING SYSTEM PARTICULARLY SUITABLE FOR LIQUIDS HAVING LOW SURFACE TENSION ALLERGAN (US) 1995-11-16 WO disclosed
WO-1995030605-A1 MULTIPLE FLUID DISPENSING DEVICE FOR LOW SURFACE TENSION FORMULATIONS ALLERGAN INC (US) 1995-11-16 WO disclosed