Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15572055 | 1.00 | CASR (0.47) | CASRADRA2CSLC6A2SLC6A4DRD2 | |
| SCHEMBL17291669 | 1.00 | CASR (0.47) | CASRADRA2CSLC6A2SLC6A4DRD2 | |
| SCHEMBL13077605 | 1.00 | CASR (0.47) | CASRADRA2CSLC6A2SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL3946213 | 0.99 | CASR (0.48) | CASRADRA2CSLC6A2SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL3945283 | 0.99 | CASR (0.48) | CASRADRA2CSLC6A2SLC6A4DRD2 | |
| SCHEMBL13077942 | 0.91 | CASR (0.44) | CASRADRA2CSLC6A2SLC6A4DRD2 | |
| SCHEMBL13077591 | 0.89 | CASR (0.43) | CASRADRA2CSLC6A2SLC6A4DRD2 | |
| SCHEMBL13077931 | 0.89 | CASR (0.43) | CASRADRA2CSLC6A2SLC6A4DRD2 | |
| SCHEMBL13077834 | 0.89 | CASR (0.43) | CASRADRA2CSLC6A2SLC6A4DRD2 | |
| SCHEMBL5501489 | 0.88 | CASR (0.45) | CASRADRA2CSLC6A2SLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344407-A1 | FENDILINE DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS, INC. | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344407-A1 | FENDILINE DERIVATIVES AND METHODS OF USE THEREOF | KRAS, RASSF5, RASSF2 | CASR 1543/4885ADRA2C 608/4885SLC6A2 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.