Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 15/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5490705 | 0.99 | F2R (0.38) | F2RCYP3A4KDM4ENPC1MAPT | |
| SCHEMBL1729142 | 0.83 | F2R (0.46) | F2RCYP3A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1730953 | 0.83 | CYP3A4 (0.40) | F2RCYP3A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5488845 | 0.83 | F2R (0.47) | F2RCYP3A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1729042 | 0.81 | F2R (0.39) | F2RCYP3A4KDM4EMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL1729307 | 0.80 | F2R (0.40) | F2RCYP3A4KDM4EMAPTRAB9A | |
| SCHEMBL14449067 | 0.79 | F2R (0.45) | F2RCYP3A4KDM4ENPC1MAPT | |
| Bromide SCHEMBL1729417 | 0.78 | F2R (0.38) | F2RCYP3A4KDM4EMAPTRAB9A | |
| Bromide SCHEMBL1728992 | 0.78 | F2R (0.39) | F2RCYP3A4KDM4ENPC1MAPT | |
| Bromide SCHEMBL1731414 | 0.78 | F2R (0.42) | F2RCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |