Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728938 | 0.88 | TRPC3 (0.55) | TRPC3MAPTTP53LMNABCHE | |
| SCHEMBL4705029 | 0.84 | CKS1B (0.56) | TRPC3MAPTTP53BCHE | |
| SCHEMBL3266160 | 0.83 | TP53 (0.50) | TRPC3MAPTTP53LMNABCHE | |
| SCHEMBL4704809 | 0.81 | TRPC3 (0.60) | TRPC3MAPTTP53LMNABCHE | |
| SCHEMBL4436265 | 0.79 | GRIN2B (0.65) | TRPC3MAPTTP53LMNABCHE | |
| SCHEMBL9369695 | 0.78 | TRPC3 (0.68) | TRPC3MAPTTP53BCHEACHE | |
| SCHEMBL4713162 | 0.78 | TRPC3 (0.68) | TRPC3MAPTTP53BCHEACHE | |
| SCHEMBL4916880 | 0.77 | TRPC3 (0.53) | TRPC3MAPTTP53 | |
| SCHEMBL4703466 | 0.76 | BCHE (0.60) | TRPC3MAPTTP53LMNABCHE | |
| SCHEMBL14587776 | 0.76 | TRPC3 (0.68) | TRPC3MAPTTP53LMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |