Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL15 | P40933 | 18/20 | 0.70 |
| ▸ | IL15RA | Q13261 | 17/20 | 0.70 |
| ▸ | CNKSR1 | Q969H4 | 2/20 | 0.52 |
| ▸ | IL2 | P60568 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17293745 | 0.87 | IL15 (0.70) | IL15IL15RACNKSR1IL2 | |
| SCHEMBL17293576 | 0.87 | IL15 (0.82) | IL15IL15RACNKSR1IL2 | |
| SCHEMBL17293612 | 0.82 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293630 | 0.82 | IL15 (0.63) | IL15IL15RACNKSR1IL2 | |
| SCHEMBL17302311 | 0.77 | IL15 (0.86) | IL15IL15RAIL2 | |
| SCHEMBL17293820 | 0.71 | IL15 (0.69) | IL15IL15RACNKSR1IL2 | |
| SCHEMBL15033150 | 0.69 | CNKSR1 (0.74) | IL15IL15RACNKSR1IL2 | |
| SCHEMBL15811545 | 0.68 | CNKSR1 (1.00) | IL15IL15RACNKSR1IL2 | |
| SCHEMBL17293792 | 0.67 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293580 | 0.66 | IL15 (1.00) | IL15IL15RACNKSR1IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181394-A1 | NOVEL IL-2/IL-15 RECEPTOR ANTAGONIST COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES OR GRAFT REJECTION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2015-12-03 | — | — | WO | claimed |
| WO-2015181394-A1 | NOVEL IL-2/IL-15 RECEPTOR ANTAGONIST COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES OR GRAFT REJECTION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2015-12-03 | — | — | WO | disclosed |