Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL15 | P40933 | 17/20 | 1.00 |
| ▸ | IL15RA | Q13261 | 12/20 | 1.00 |
| ▸ | IL2 | P60568 | 6/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17293574 | 1.00 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293662 | 1.00 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293753 | 1.00 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293615 | 0.98 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293542 | 0.93 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293580 | 0.90 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293445 | 0.87 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293831 | 0.87 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293792 | 0.86 | IL15 (1.00) | IL15IL15RAIL2 | |
| SCHEMBL17293839 | 0.86 | IL15 (1.00) | IL15IL15RAIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181394-A1 | NOVEL IL-2/IL-15 RECEPTOR ANTAGONIST COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES OR GRAFT REJECTION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2015-12-03 | — | — | WO | claimed |
| WO-2015181394-A1 | NOVEL IL-2/IL-15 RECEPTOR ANTAGONIST COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES OR GRAFT REJECTION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2015-12-03 | — | — | WO | disclosed |