Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.40 |
| ▸ | FNTB | P49356 | 8/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295461 | 0.91 | LTB4R2 (0.36) | FNTAFNTBPGGT1BLTB4R2LPAR1 | |
| SCHEMBL17295151 | 0.90 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL17295300 | 0.89 | FNTA (0.41) | FNTAFNTBPGGT1BLTB4R2 | |
| SCHEMBL17295206 | 0.87 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL17295235 | 0.84 | FNTA (0.42) | FNTAFNTBPGGT1B | |
| SCHEMBL17295207 | 0.84 | FNTA (0.53) | FNTAFNTBPGGT1B | |
| SCHEMBL17295342 | 0.82 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL17301900 | 0.81 | FNTA (0.40) | FNTAFNTBPGGT1B | |
| SCHEMBL17301808 | 0.81 | FNTA (0.42) | FNTAFNTBPGGT1BLTB4R2 | |
| SCHEMBL17295383 | 0.81 | FNTA (0.47) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181272-A1 | RAB GERANYLGERANYL TRANSFERASE INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2015-12-03 | — | — | WO | claimed |
| WO-2015181272-A1 | RAB GERANYLGERANYL TRANSFERASE INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2015-12-03 | — | — | WO | disclosed |