Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729547 | 1.00 | F2R (0.39) | F2REGFRKMT2AMEN1KDM4E | |
| Bromide SCHEMBL5484064 | 0.99 | F2R (0.39) | F2REGFRKMT2AMEN1KDM4E | |
| Bromide SCHEMBL5484063 | 0.99 | F2R (0.39) | F2REGFRKMT2AMEN1KDM4E | |
| Bromide SCHEMBL1730963 | 0.92 | F2R (0.36) | F2RKMT2AMEN1KDM4EMAPT | |
| Bromide SCHEMBL1730965 | 0.92 | F2R (0.36) | F2RKMT2AMEN1KDM4EMAPT | |
| Bromide SCHEMBL1729504 | 0.88 | F2R (0.37) | F2RKDM4EMAPTRAB9ACYP3A4 | |
| Bromide SCHEMBL1729505 | 0.88 | F2R (0.37) | F2RKDM4EMAPTRAB9ACYP3A4 | |
| Bromide SCHEMBL1730821 | 0.87 | F2R (0.36) | F2RKDM4EMAPTRAB9ACYP3A4 | |
| Bromide SCHEMBL1730819 | 0.87 | F2R (0.36) | F2RKDM4EMAPTRAB9ACYP3A4 | |
| Bromide SCHEMBL1729528 | 0.82 | F2R (0.46) | F2RKMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |