⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30675853 | 0.96 | — | — | |
| SCHEMBL1305051 | 0.87 | — | — | |
| SCHEMBL457715 | 0.79 | — | — | |
| SCHEMBL470814 | 0.79 | — | — | |
| SCHEMBL2596793 | 0.79 | — | — | |
| SCHEMBL31424325 | 0.78 | — | — | |
| SCHEMBL26505305 | 0.74 | KDM1A (0.34) | — | |
| SCHEMBL22570231 | 0.74 | KDM1A (0.34) | — | |
| SCHEMBL26402682 | 0.73 | CHRM2 (0.41) | — | |
| SCHEMBL10140982 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025302-A | Synthesis method of Fmoc-L-4' -tetrahydropyranyl glycine | 康化（上海）新药研发有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-115011974-B | Method for preparing trans-allylbenzene compound by electrocatalytic reaction | 哈尔滨工业大学（深圳） | 2023-08-04 | — | — | CN | claimed |
| CN-114645288-B | Preparation method of trans-olefin compound | 哈尔滨工业大学（深圳） | 2023-08-01 | — | — | CN | claimed |
| CN-115011974-A | Method for preparing trans-allyl benzene compound through electrocatalysis | 哈尔滨工业大学（深圳） | 2022-09-06 | — | — | CN | claimed |
| CN-114645288-A | Preparation method of trans-olefin compound | 哈尔滨工业大学（深圳） | 2022-06-21 | — | — | CN | claimed |
| CN-108689976-B | Method for synthesizing 4-iodo-tetrahydropyran derivative under catalysis of 5-sulfosalicylic acid and dichlorotitanocene | 陕西师范大学 | 2021-12-28 | — | — | CN | claimed |
| CN-108689976-A | The method that 5-sulphosalicylic acid collaboration cyclopentadienyl titanium dichloride catalyzes and synthesizes 4- iodo tetrahydropyran derivatives | 陕西师范大学 | 2018-10-23 | — | — | CN | claimed |
| US-3931236-A | Oxidation and dehydrohalogenation of halotetrahydropyrans | PHILLIPS PETROLEUM COMPANY (US) | 1976-01-06 | — | — | US | claimed |
| US-12606544-B2 | JAK1 selective kinase inhibitor | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2026-04-21 | — | — | US | disclosed |
| US-20260102383-A1 | LPAR1 Inhibitors | ABBVIE INC (US) | 2026-04-16 | — | — | US | disclosed |
| EP-4724435-A1 | BIFUNCTIONAL AZINES CONJOGATES AS SELECTIVE DEGRADERS OF SMARCA2 AND THERAPEUTIC USES THEREOF | Nurix Therapeutics, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| US-20260098028-A1 | Compounds and Their Use for Treatment of Hemoglobinopathies | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-04-09 | — | — | US | disclosed |
| EP-4680607-A1 | BICYCLIC UREAS AS KINASE INHIBITORS | Incyte Corporation (US) | 2026-01-21 | — | — | EP | disclosed |
| US-12492194-B2 | HPK1 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2025-12-09 | — | — | US | disclosed |
| WO-2004072031-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | PROSIDION LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |
| US-6635639-B2 | Treatment or diagnosis of central nervous system conditions | NPS ALLELIX CORP. (CA) | 2003-10-21 | — | — | US | disclosed |
| US-20020169322-A1 | Use of N-alkylamino-heterocylic compounds for the treatment of migraine | NPS ALLEXLIX CORP. | 2002-11-14 | — | — | US | disclosed |
| US-6380242-B1 | FOR DIAGNOSIS AND THERAPY OF CENTRAL NERVOUS SYSTEM CONDITIONS | NPS ALLELIX CORP. (CA) | 2002-04-30 | — | — | US | disclosed |
| EP-1140074-A1 | INDOLE AND INDOLIZIDINE DERIVATIVES FOR THE TREATMENT OF MIGRAINE | NPS Allelix Corp. (CA) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038677-A1 | INDOLE AND INDOLIZIDINE DERIVATIVES FOR THE TREATMENT OF MIGRAINE | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-07-06 | — | — | WO | disclosed |