Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1731971 | 0.99 | F2R (0.54) | F2RMAPTTHRBMEN1KDM4A | |
| Bromide SCHEMBL5484925 | 0.89 | F2R (0.51) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1730981 | 0.87 | F2R (0.49) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1732128 | 0.86 | F2R (0.54) | F2RMAPTTHRBSMN1; SMN2KDM4E | |
| Bromide SCHEMBL1730041 | 0.85 | F2R (0.52) | F2RMAPTTHRBMEN1KMT2A | |
| SCHEMBL27527338 | 0.84 | F2R (0.41) | F2RMAPTTHRBMEN1KDM4A | |
| Bromide SCHEMBL5484900 | 0.83 | F2R (0.51) | F2RMAPTTHRBKDM4ENPC1 | |
| Bromide SCHEMBL1730216 | 0.83 | F2R (0.49) | F2RMAPTKDM4ENPC1RAB9A | |
| SCHEMBL27505739 | 0.82 | F2R (0.52) | F2RMAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL27508138 | 0.82 | F2R (0.50) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |