Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352500 | 0.89 | CHRM1 (0.54) | CHRM1 | |
| SCHEMBL17296541 | 0.89 | CHRM1 (0.50) | CHRM1 | |
| SCHEMBL12803543 | 0.88 | CHRM1 (0.68) | CHRM1KCNH2 | |
| SCHEMBL12802614 | 0.88 | CHRM1 (0.59) | CHRM1KCNH2 | |
| SCHEMBL6890674 | 0.85 | CHRM1 (0.49) | CHRM1KCNH2 | |
| SCHEMBL17656781 | 0.84 | CHRM1 (0.45) | CHRM1 | |
| SCHEMBL12803319 | 0.83 | CHRM1 (0.60) | CHRM1KCNH2 | |
| SCHEMBL12803346 | 0.82 | CHRM1 (0.54) | CHRM1 | |
| SCHEMBL18756162 | 0.81 | CHRM1 (0.58) | CHRM1KCNH2 | |
| SCHEMBL21545830 | 0.81 | CHRM1 (0.75) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199939-B2 | Quinoline amide M1 receptor positive allosteric modulators | MERCK SHARP & DOHME CORP. (US) | 2015-12-01 | — | — | US | disclosed |