Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | BCHE | P06276 | 5/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265477 | 0.86 | HRH3 (0.49) | HRH3ACHEBCHECHRM4ACACB | |
| SCHEMBL3269870 | 0.85 | HRH3 (0.48) | HRH3ACHEBCHECHRM4ACACB | |
| SCHEMBL1728885 | 0.85 | CHRM4 (0.53) | ACHEBCHECHRM4ENPP1 | |
| SCHEMBL3266792 | 0.84 | HRH3 (0.48) | HRH3ACHEBCHECHRM4ACACB | |
| SCHEMBL345345 | 0.84 | HRH3 (0.50) | HRH3CHRM4TP53 | |
| SCHEMBL346050 | 0.84 | HRH3 (0.56) | HRH3CHRM4ACACB | |
| SCHEMBL3266113 | 0.84 | HRH3 (0.47) | HRH3ACHEBCHECHRM4ACACB | |
| SCHEMBL1727542 | 0.82 | HRH3 (0.52) | HRH3ALDH1A1 | |
| SCHEMBL14797149 | 0.81 | CHRM4 (0.47) | ACHEBCHECHRM4MAPTKMT2A | |
| SCHEMBL1727774 | 0.81 | HRH3 (0.48) | HRH3ACHEBCHECHRM4ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |