Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729930 | 0.83 | KDM4E (0.33) | F2RKDM4EMAPTRAB9ANPC1 | |
| Bromide SCHEMBL1730770 | 0.82 | F2R (0.54) | F2RKDM4EMAPTRAB9ANPC1 | |
| Bromide SCHEMBL1732635 | 0.81 | F2R (0.46) | F2RKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL14449091 | 0.80 | F2R (0.41) | F2RKDM4EMAPTRAB9ASMN1; SMN2 | |
| Bromide SCHEMBL1732345 | 0.80 | F2R (0.46) | F2RKDM4EMAPTRAB9ANPC1 | |
| Bromide SCHEMBL1730967 | 0.80 | F2R (0.46) | F2RKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL1731009 | 0.79 | F2R (0.40) | F2RMAPT | |
| Trifluoroacetic Acid SCHEMBL5490918 | 0.78 | F2R (0.44) | F2R | |
| Bromide SCHEMBL1730628 | 0.78 | F2R (0.45) | F2R | |
| Bromide SCHEMBL1732156 | 0.78 | F2R (0.43) | F2RKDM4EMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |