SCHEMBL1730098

SCHEMBL1730098

COC(=O)O[C@@H]1CS[C@H]2C[C@@](CO)(NC(=O)OC(C)(C)C)C(=O)N21

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPIA P62937 1/20 0.32
GFER P55789 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1728242 0.90 DPP4 (0.35) PPIAGFER
SCHEMBL1728385 0.90 DPP4 (0.35) PPIAGFER
SCHEMBL1728832 0.90 DPP4 (0.35) PPIAGFER
SCHEMBL1729814 0.88 PPIA (0.30) PPIAGFER
SCHEMBL1728337 0.88 PPIA (0.30) PPIAGFER
SCHEMBL5770627 0.88 PPIA (0.30) PPIAGFER
SCHEMBL1728447 0.88 PPIA (0.30) PPIAGFER
SCHEMBL1729957 0.87 PPIA (0.33) PPIA
SCHEMBL1730373 0.86 PPIA (0.41) PPIADPP8DPP9
SCHEMBL8294822 0.83 PPIA (0.31) PPIADPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651653-B1 NOVEL CYANO THIAZOLIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT SANOFI AVENTIS DEUTSCHLAND (DE) 2011-11-23 EP disclosed
EP-1651653-A1 NOVEL CYANO THIAZOLIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT Sanofi-Aventis Deutschland GmbH (DE) 2006-05-03 EP disclosed
WO-2005012312-A1 NOVEL CYANO THIAZOLIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2005-02-10 WO disclosed