SCHEMBL17301285

SCHEMBL17301285

C=CC(=O)OCCCCCCOc1ccc(-c2ccc(C(=O)Oc3ccc(OC(=O)c4ccc(-c5ccc(OCCCCCCOC(=O)C=C)cc5)cc4)c(C)c3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.43
PPARD Q03181 1/20 0.43
PPARA Q07869 1/20 0.43
HTT P42858 3/20 0.41
RARB P10826 3/20 0.41
MAPT P10636 2/20 0.41
NPC1 O15118 2/20 0.41
LMNA P02545 2/20 0.41
THRB P10828 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP3A4 P08684 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
KCNH2 Q12809 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23071727 1.00 PPARG (0.43) PPARGPPARDPPARAHTTRARB
SCHEMBL17301282 0.99 PPARG (0.44) PPARGPPARDPPARAHTTRARB
SCHEMBL17301281 0.97 PPARG (0.47) PPARGPPARDPPARAHTTMAPT
SCHEMBL9106264 0.97 HTT (0.44) PPARGPPARDPPARAHTTMAPT
SCHEMBL17721435 0.97 HTT (0.44) PPARGPPARDPPARAHTTMAPT
SCHEMBL9110786 0.97 HTT (0.44) PPARGPPARDPPARAHTTMAPT
SCHEMBL14426393 0.97 HTT (0.44) PPARGPPARDPPARAHTTMAPT
SCHEMBL9106590 0.97 HTT (0.44) PPARGPPARDPPARAHTTMAPT
SCHEMBL16674100 0.97 HTT (0.44) PPARGPPARDPPARAHTTMAPT
SCHEMBL16674101 0.97 HTT (0.44) PPARGPPARDPPARAHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634638-B2 Liquid crystal composition, reflective layer, method for producing reflective layer, and copolymer FUJIFILM CORPORATION (JP) 2023-04-25 US disclosed
US-11332671-B2 Liquid crystal composition, method for producing reflective layer, reflective layer, cured product, and optically anisotropic body FUJIFILM CORPORATION (JP) 2022-05-17 US disclosed
US-11209688-B2 Reflective layer obtained by immobilizing cholesteric liquid crystalline phase FUJIFILM CORPORATION (JP) 2021-12-28 US disclosed
US-10942438-B2 Structure and method of manufacturing structure FUJIFILM CORPORATION (JP) 2021-03-09 US disclosed
US-20200231874-A1 LIQUID CRYSTAL COMPOSITION, REFLECTIVE LAYER, METHOD FOR PRODUCING REFLECTIVE LAYER, AND COPOLYMER FUJIFILM CORPORATION (JP) 2020-07-23 US disclosed
US-20200102500-A1 LIQUID CRYSTAL COMPOSITION, METHOD FOR PRODUCING REFLECTIVE LAYER, REFLECTIVE LAYER, CURED PRODUCT, AND OPTICALLY ANISOTROPIC BODY FUJIFILM CORPORATION (JP) 2020-04-02 US disclosed
US-20190033634-A1 METHOD FOR PRODUCING REFLECTIVE LAYER AND REFLECTIVE LAYER FUJIFILM CORPORATION (JP) 2019-01-31 US disclosed
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US disclosed
US-9006450-B2 Compounds, pharmaceutical compositions and uses thereof BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-04-14 US disclosed