SCHEMBL17301910

SCHEMBL17301910

Cc1cc(C#N)ccc1N(CCCc1ccc(Br)cc1)Cc1cncn1C

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 16/20 0.43
FNTB P49356 16/20 0.43
PGGT1B P53609 13/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17302058 0.90 FNTA (0.49) FNTAFNTBPGGT1B
SCHEMBL17301918 0.87 FNTA (0.39) FNTAFNTBPGGT1B
SCHEMBL17295141 0.86 FNTA (0.55) FNTAFNTBPGGT1B
SCHEMBL17302061 0.83 FNTA (0.41) FNTAFNTBPGGT1B
SCHEMBL17295308 0.83 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL17301901 0.83 FNTA (0.44) FNTAFNTBPGGT1B
SCHEMBL17302057 0.82 FNTA (0.45) FNTAFNTBPGGT1B
SCHEMBL17295235 0.81 FNTA (0.42) FNTAFNTBPGGT1B
SCHEMBL17302062 0.81 FNTA (0.41) FNTAFNTBPGGT1B
SCHEMBL17301900 0.80 FNTA (0.40) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015181272-A1 RAB GERANYLGERANYL TRANSFERASE INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2015-12-03 WO disclosed