Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 15/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5481445 | 0.99 | F2R (0.46) | F2RCYP1A1CYP1A2CYP2D6CYP1B1 | |
| Bromide SCHEMBL1730631 | 0.88 | F2R (0.52) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732302 | 0.87 | F2R (0.45) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732111 | 0.86 | F2R (0.46) | F2R | |
| SCHEMBL1729743 | 0.86 | F2R (0.48) | F2RMAPTCYP3A4 | |
| SCHEMBL14449121 | 0.85 | F2R (0.49) | F2RCYP3A4 | |
| Trifluoroacetic Acid SCHEMBL1729328 | 0.85 | F2R (0.51) | F2RMAPT | |
| Bromide SCHEMBL1732795 | 0.85 | F2R (0.47) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732515 | 0.85 | F2R (0.49) | F2RKDM4ENPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL1730634 | 0.85 | F2R (0.49) | F2RCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951502-B2 | Method of dynamic nuclear polarisation (DNP) | GE HEALTHCARE AS (NO) | 2015-02-10 | — | — | US | disclosed |
| EP-1954321-B1 | METHOD OF DYNAMIC NUCLEAR POLARISATION (DNP) USING A TRITYL RADICAL AND A PARAMAGNETIC METAL ION | GE HEALTHCARE AS (NO) | 2011-11-23 | — | — | EP | disclosed |
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1954321-A2 | METHOD OF DYNAMIC NUCLEAR POLARISATION (DNP) USING A TRITYL RADICAL AND A PARAMAGNETIC METAL ION | GE Healthcare AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007064226-A2 | METHOD OF DYNAMIC NUCLEAR POLARISATION (DNP) USING A TRITYL RADICAL AND A PARAMAGNETIC METAL ION | GE HEALTHCARE AS (NO) | 2007-06-07 | — | — | WO | disclosed |