Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.74 |
| ▸ | BRD2 | P25440 | 1/20 | 0.74 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.74 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.74 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17296513 | 0.88 | BRD4 (0.85) | BRD4BRD2BRD3CREBBPBCHE | |
| SCHEMBL17302662 | 0.86 | BRD4 (0.94) | BRD4BRD2BRD3CREBBPBCHE | |
| SCHEMBL16771423 | 0.85 | BRD4 (1.00) | BRD4BRD2BRD3CREBBPBCHE | |
| SCHEMBL17296523 | 0.84 | BRD4 (0.98) | BRD4BRD2BRD3CREBBPBCHE | |
| SCHEMBL1391 | 0.80 | BRD4 (0.64) | BRD4BRD2BRD3CREBBPBCHE | |
| SCHEMBL18752063 | 0.80 | BRD4 (0.52) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL18729721 | 0.78 | BRD4 (0.69) | BRD4BRD2BRD3CREBBPBCHE | |
| SCHEMBL17302648 | 0.76 | BRD4 (0.56) | BRD4BRD2BRD3CREBBPBCHE | |
| SCHEMBL17302667 | 0.76 | BRD4 (0.64) | BRD4BRD2BRD3CREBBPBCHE | |
| SCHEMBL588 | 0.76 | BCHE (0.69) | BRD4BRD2BRD3CREBBPBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184257-A2 | SMALL MOLECULE TRANSCRIPTION MODULATORS OF BROMODOMAINS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2015-12-03 | — | — | WO | disclosed |