Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 17/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730387 | 1.00 | F2R (0.68) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731034 | 0.99 | F2R (0.68) | F2RKDM4ENPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL1728959 | 0.99 | F2R (0.68) | F2R | |
| Bromide SCHEMBL1731792 | 0.95 | F2R (0.71) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449196 | 0.94 | F2R (0.65) | F2R | |
| SCHEMBL12151774 | 0.93 | F2R (0.67) | F2R | |
| Hydrochloric Acid SCHEMBL1730886 | 0.93 | F2R (0.66) | F2R | |
| SCHEMBL14449190 | 0.92 | F2R (0.68) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732397 | 0.92 | F2R (0.57) | F2RKDM4ENPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL1728865 | 0.91 | F2R (0.69) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1614680-A2 | Process for preparing 2-iminopyrrolidine derivatives | Eisai Co., Ltd. (JP) | 2006-01-11 | — | — | EP | disclosed |