SCHEMBL17304168

SCHEMBL17304168

Nc1nc2c(ncn2[C@@H]2O[C@@H]3COP(=O)(O)O[C@H]4C(O)[C@@H](COP(=O)(O)O[C@H]2C3O)O[C@H]4n2cnc3c(N)ncnc32)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29460466 1.00 STING1 (1.00) STING1
SCHEMBL16219984 1.00 STING1 (1.00) STING1
SCHEMBL21160982 1.00 STING1 (1.00) STING1
SCHEMBL17577454 1.00 STING1 (1.00) STING1
SCHEMBL23477351 0.97 STING1 (1.00) STING1
SCHEMBL22434473 0.97 STING1 (1.00) STING1
SCHEMBL22334110 0.97 STING1 (1.00) STING1
SCHEMBL24967640 0.97 STING1 (1.00) STING1
SCHEMBL22334105 0.97 STING1 (1.00) STING1
SCHEMBL21305065 0.97 STING1 (1.00) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150343056-A1 PHARMACEUTICAL TARGETING OF A MAMMALIAN CYCLIC DI-NUCLEOTIDE SIGNALING PATHWAY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150343056-A1 PHARMACEUTICAL TARGETING OF A MAMMALIAN CYCLIC DI-NUCLEOTIDE SIGNALING PATHWAY CGAS, GMPS, STING1 STING1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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