SCHEMBL1730422

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1730855	0.89	GSK3B (0.38)	GSK3BTHRATHRBSCN1ASCN2A
	SCHEMBL1730596	0.89	GSK3B (0.38)	GSK3BSCN1ASCN2ASCN3AKDM4E
	SCHEMBL2772923	0.87	TNFRSF1A (0.48)	GSK3BTNFRSF1ACYP3A4LMNARECQL
	SCHEMBL1730810	0.82	TNFRSF1A (0.42)	TNFRSF1ACYP3A4LMNARECQLPTGS2
	SCHEMBL1730641	0.77	NCOA1 (0.49)	LMNAF2RKDM4EMEN1ALDH1A1
	SCHEMBL12187801	0.76	F2R (0.46)	GSK3BF2RMEN1KMT2A
	SCHEMBL12187575	0.76	GSK3B (0.38)	GSK3BTNFRSF1ACYP3A4KDM4EMEN1
	SCHEMBL12187442	0.76	F2R (0.45)	F2RKDM4EMEN1ALDH1A1KMT2A
	SCHEMBL1205566	0.75	F2R (0.42)	GSK3BTNFRSF1ATHRATHRBLMNA
	SCHEMBL1730605	0.75	GSK3B (0.37)	GSK3BTNFRSF1ACYP3A4PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.