⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758279 | 0.82 | — | — | |
| SCHEMBL11320412 | 0.76 | GABRR1 (0.40) | — | |
| SCHEMBL8471198 | 0.74 | — | — | |
| SCHEMBL12631959 | 0.74 | — | — | |
| SCHEMBL7364807 | 0.74 | — | — | |
| SCHEMBL25210679 | 0.74 | — | — | |
| SCHEMBL7364812 | 0.74 | — | — | |
| SCHEMBL3686870 | 0.74 | — | — | |
| SCHEMBL103243 | 0.74 | — | — | |
| SCHEMBL25332218 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344426-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | ALZHEIMER'S INSTITUTE OF AMERICA, INC. (US) | 2015-12-03 | — | — | US | disclosed |