Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 15/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1730552 | 0.99 | F2R (0.61) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449044 | 0.93 | F2R (0.71) | F2R | |
| SCHEMBL1729520 | 0.92 | F2R (0.57) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730903 | 0.92 | F2R (0.69) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730448 | 0.92 | F2R (0.71) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731495 | 0.91 | F2R (0.56) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL5482743 | 0.91 | F2R (0.57) | F2RKDM4ENPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL1729249 | 0.90 | F2R (0.63) | F2R | |
| Bromide SCHEMBL1731657 | 0.88 | F2R (0.55) | F2R | |
| SCHEMBL14449113 | 0.88 | F2R (0.61) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| EP-1614680-A2 | Process for preparing 2-iminopyrrolidine derivatives | Eisai Co., Ltd. (JP) | 2006-01-11 | — | — | EP | disclosed |