SCHEMBL17305

SCHEMBL17305

CC1(COc2ccc(Cc3cc([C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)ccc3Cl)cc2)CCCCC1

nearest known ligand 0.82

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.82
SLC5A1 P13866 17/20 0.82
ADRA2A P08913 1/20 0.72
SLC5A11 Q8WWX8 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18128 0.99 SLC5A2 (0.84) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18772 0.99 SLC5A2 (0.84) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL16572157 0.97 SLC5A2 (0.84) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18014 0.91 SLC5A2 (0.80) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18219 0.91 SLC5A2 (0.80) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL16572216 0.90 SLC5A2 (1.00) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL19415585 0.90 SLC5A2 (1.00) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18283 0.90 SLC5A2 (0.73) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL24323 0.89 SLC5A2 (0.74) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL17530 0.89 SLC5A2 (0.74) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025857-A1 CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS HETERO RESEARCH FOUNDATION (IN) 2012-03-01 WO disclosed
WO-2012025857-A1 CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS HETERO RESEARCH FOUNDATION (IN) 2012-03-01 WO disclosed