Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306667 | 0.92 | MEN1 (0.50) | WHR1MEN1KMT2AATMDHFR | |
| SCHEMBL17307033 | 0.92 | MEN1 (0.50) | WHR1MEN1KMT2AATMDHFR | |
| SCHEMBL17306738 | 0.88 | MEN1 (0.49) | WHR1MEN1KMT2AATMDHFR | |
| SCHEMBL17306743 | 0.88 | MEN1 (0.49) | WHR1MEN1KMT2AATMDHFR | |
| SCHEMBL17306462 | 0.88 | MEN1 (0.49) | WHR1MEN1KMT2AATMDHFR | |
| SCHEMBL17306599 | 0.86 | MEN1 (0.55) | WHR1MEN1KMT2AATMDHFR | |
| SCHEMBL17307026 | 0.85 | DHODH (0.44) | WHR1MEN1KMT2AATMDHFR | |
| SCHEMBL17307047 | 0.83 | CYP19A1 (0.49) | WHR1MEN1KMT2AATMDHFR | |
| SCHEMBL17306873 | 0.83 | CYP19A1 (0.49) | WHR1MEN1KMT2AATMDHFR | |
| SCHEMBL17306768 | 0.82 | WHR1 (0.48) | WHR1MEN1KMT2AATMDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |