Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | WHR1 | P49842 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306607 | 0.94 | MEN1 (0.40) | HPGDMEN1KMT2AATMHPGDS | |
| SCHEMBL17306685 | 0.93 | HPGD (0.43) | HPGDMEN1KMT2AATMHPGDS | |
| SCHEMBL17306453 | 0.92 | HPGD (0.45) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL17306589 | 0.92 | HPGD (0.47) | HPGDMEN1KMT2AATMMKNK1 | |
| SCHEMBL17307085 | 0.88 | PIK3CA (0.42) | HPGDMEN1KMT2AATMHPGDS | |
| SCHEMBL17306658 | 0.88 | MEN1 (0.46) | HPGDMEN1KMT2AATMALK | |
| SCHEMBL17306606 | 0.88 | MEN1 (0.46) | HPGDMEN1KMT2AATMALK | |
| SCHEMBL17307040 | 0.88 | MEN1 (0.46) | HPGDMEN1KMT2AATMALK | |
| SCHEMBL17306637 | 0.88 | MEN1 (0.46) | HPGDMEN1KMT2AATMHPGDS | |
| SCHEMBL17306439 | 0.87 | HPGD (0.47) | HPGDMEN1KMT2AATMHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |