Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | WHR1 | P49842 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306615 | 0.95 | MEN1 (0.48) | MEN1KMT2AATMWHR1CYP11B1 | |
| SCHEMBL17306731 | 0.94 | MEN1 (0.49) | MEN1KMT2AATMWHR1CYP11B1 | |
| SCHEMBL17306596 | 0.85 | MEN1 (0.41) | MEN1KMT2AATMWHR1CYP11B1 | |
| SCHEMBL17306771 | 0.85 | MEN1 (0.39) | MEN1KMT2AATMWHR1CYP11B1 | |
| SCHEMBL17306599 | 0.83 | MEN1 (0.55) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306709 | 0.83 | MEN1 (0.43) | MEN1KMT2AATMWHR1CYP11B1 | |
| SCHEMBL17306681 | 0.83 | ATM (0.48) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306865 | 0.83 | MEN1 (0.39) | MEN1KMT2AATMWHR1CYP11B1 | |
| SCHEMBL17306872 | 0.83 | MEN1 (0.43) | MEN1KMT2AATMWHR1DHFR | |
| SCHEMBL17306799 | 0.83 | KMT2A (0.47) | MEN1KMT2AATMWHR1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |