Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | WHR1 | P49842 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306803 | 0.93 | MEN1 (0.42) | ATMMEN1KMT2AWHR1CA12 | |
| SCHEMBL17306681 | 0.91 | ATM (0.48) | ATMMEN1KMT2AWHR1CA12 | |
| SCHEMBL18504015 | 0.88 | MEN1 (0.54) | ATMMEN1KMT2AWHR1CA12 | |
| SCHEMBL17307093 | 0.87 | KMT2A (0.53) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL18503977 | 0.86 | MEN1 (0.55) | ATMMEN1KMT2AWHR1CA12 | |
| SCHEMBL17306709 | 0.86 | MEN1 (0.43) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL18504111 | 0.85 | ATM (0.54) | ATMMEN1KMT2AWHR1CA12 | |
| SCHEMBL17306799 | 0.85 | KMT2A (0.47) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL17307075 | 0.85 | MAPT (0.38) | ATMMEN1KMT2AWHR1ALDH1A1 | |
| SCHEMBL18504108 | 0.84 | ATM (0.55) | ATMMEN1KMT2AWHR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |