Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | WHR1 | P49842 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306636 | 0.88 | MEN1 (0.47) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17306709 | 0.88 | MEN1 (0.43) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17279443 | 0.86 | MEN1 (0.50) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17279492 | 0.86 | MEN1 (0.50) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17279440 | 0.83 | MEN1 (0.48) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17279450 | 0.83 | MEN1 (0.48) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17279451 | 0.83 | MEN1 (0.48) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17279462 | 0.83 | MEN1 (0.48) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17279491 | 0.83 | MAPT (0.45) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18327621 | 0.83 | MAPT (0.44) | MAPTLMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |