Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 3/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307097 | 1.00 | CYP2A6 (0.43) | CYP2A6PIM1PIM2CYP19A1LMNA | |
| SCHEMBL17307063 | 0.95 | CYP2A6 (0.49) | CYP2A6PIM1PIM2CYP19A1LMNA | |
| SCHEMBL17307085 | 0.94 | PIK3CA (0.42) | PIM1LMNAMAPK1HIF1ANPC1 | |
| SCHEMBL17306683 | 0.94 | CYP2A6 (0.48) | CYP2A6PIM1PIM2CYP19A1LMNA | |
| SCHEMBL17306760 | 0.94 | CYP2A6 (0.48) | CYP2A6PIM1PIM2CYP19A1LMNA | |
| SCHEMBL17306685 | 0.93 | HPGD (0.43) | CYP2A6PIM1PIM2CYP19A1HIF1A | |
| SCHEMBL17306447 | 0.91 | MTOR (0.41) | LMNAMAPK1HIF1ANPC1TP53 | |
| SCHEMBL17307061 | 0.89 | CYP1A2 (0.46) | CYP2A6PIM1CYP19A1LMNACYP1A2 | |
| SCHEMBL17306718 | 0.89 | CYP19A1 (0.48) | PIM1CYP19A1LMNACYP1A2CYP3A4 | |
| SCHEMBL17306686 | 0.88 | CYP1A2 (0.45) | CYP2A6PIM1CYP19A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015182769-A1 | QUINAZOLINE AND BENZOQUINAZOLINE COMPOUNDS AND PRODUCTION AND USE OF SAME | 東ソー株式会社 | 2015-12-03 | — | — | WO | disclosed |