Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5482722 | 0.99 | F2R (0.61) | F2RHTTLMNAPOLBALOX15 | |
| SCHEMBL1730236 | 0.90 | F2R (0.61) | F2RHTTLMNAPOLBMAPT | |
| Bromide SCHEMBL5484907 | 0.89 | F2R (0.61) | F2RHTTLMNAPOLBMAPT | |
| SCHEMBL1730513 | 0.89 | F2R (0.74) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1730070 | 0.89 | F2R (0.60) | F2RHTTLMNAMAPTKDM4E | |
| SCHEMBL1729331 | 0.88 | F2R (0.67) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1730449 | 0.88 | F2R (0.75) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1730669 | 0.87 | F2R (0.59) | F2RMAPTKDM4ENPC1RAB9A | |
| SCHEMBL12151716 | 0.87 | F2R (0.66) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1728708 | 0.87 | F2R (0.67) | F2RMAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |