Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 8/20 | 0.78 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17310168 | 0.90 | ALK (0.72) | ALK | |
| SCHEMBL15933042 | 0.87 | ALK (1.00) | ALKPDE10A | |
| SCHEMBL17310124 | 0.84 | ALK (0.64) | ALK | |
| SCHEMBL15933040 | 0.81 | ALK (0.88) | ALKPDE10A | |
| SCHEMBL17310036 | 0.80 | ALK (0.70) | ALKTRPC6 | |
| SCHEMBL17310234 | 0.79 | ALK (0.60) | ALK | |
| SCHEMBL15933047 | 0.78 | ALK (0.59) | ALKPDE10A | |
| SCHEMBL17404654 | 0.78 | ALK (0.69) | ALKPDE10A | |
| SCHEMBL17310051 | 0.77 | ALK (0.55) | ALK | |
| SCHEMBL15933043 | 0.76 | ALK (1.00) | ALKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2952510-B1 | SUBSTITUTED 2-AMINOPYRIDINE PROTEIN KINASE INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2018-12-26 | — | — | EP | disclosed |
| EP-2952510-A1 | SUBSTITUTED 2-AMINOPYRIDINE PROTEIN KINASE INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co.,Ltd (CN) | 2015-12-09 | — | — | EP | disclosed |