Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 18/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1729136 | 0.99 | F2R (0.79) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL5484851 | 0.97 | F2R (0.76) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449141 | 0.96 | F2R (0.72) | F2RMAPTALDH1A1GAA | |
| Bromide SCHEMBL1729239 | 0.95 | F2R (0.73) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731835 | 0.94 | F2R (0.73) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449156 | 0.94 | F2R (0.71) | F2RKDM4ERAB9A | |
| SCHEMBL14449144 | 0.94 | F2R (0.73) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1728717 | 0.94 | F2R (0.71) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730758 | 0.94 | F2R (0.74) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL1728787 | 0.93 | F2R (0.74) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| EP-1614680-A2 | Process for preparing 2-iminopyrrolidine derivatives | Eisai Co., Ltd. (JP) | 2006-01-11 | — | — | EP | disclosed |