Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSK | P41240 | 3/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | ABL1 | P00519 | 10/20 | 0.53 |
| ▸ | BCR | P11274 | 7/20 | 0.53 |
| ▸ | LYN | P07948 | 3/20 | 0.53 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.53 |
| ▸ | BRAF | P15056 | 2/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.53 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | ARAF | P10398 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.53 |
| ▸ | ABL2 | P42684 | 1/20 | 0.53 |
| ▸ | FRK | P42685 | 1/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15859941 | 1.00 | CSK (0.56) | CSKMAPK14ABL1BCRLYN | |
| SCHEMBL18403051 | 0.93 | CSK (0.49) | CSKMAPK14ABL1BCRLYN | |
| SCHEMBL17324268 | 0.92 | CSK (0.48) | CSKMAPK14ABL1BCRLYN | |
| SCHEMBL3814061 | 0.92 | CSK (0.59) | CSKMAPK14ABL1BCRLYN | |
| SCHEMBL17313594 | 0.90 | CSK (0.59) | CSKMAPK14ABL1BCRLYN | |
| SCHEMBL17324210 | 0.90 | CSK (0.59) | CSKMAPK14ABL1BCRLYN | |
| SCHEMBL17313578 | 0.89 | CSK (0.57) | CSKMAPK14ABL1BCRLYN | |
| SCHEMBL17324137 | 0.89 | CSK (0.57) | CSKMAPK14ABL1BCRLYN | |
| SCHEMBL15860005 | 0.89 | BRAF (0.56) | ABL1BRAFEGFR | |
| SCHEMBL18403050 | 0.89 | EGFR (0.46) | CSKMAPK14ABL1BCRLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550772-B2 | Azaindole derivatives as multi kinase inhibitors | ORIBASE PHARMA (FR) | 2017-01-24 | — | — | US | disclosed |
| US-20150353539-A1 | AZAINDOLE DERIVATIVES AS MULTI KINASE INHIBITORS | ORIBASE PHARMA (FR) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353539-A1 | AZAINDOLE DERIVATIVES AS MULTI KINASE INHIBITORS | MAP2K2, MAP2K5, MAP2K3 | CSK 130/4885MAPK14 143/4885ABL1 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.