Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 11/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5484051 | 0.99 | PDE4B (0.36) | PDE4BF2RPTPN1CYP3A4 | |
| Bromide SCHEMBL1731593 | 0.93 | F2R (0.35) | PDE4BF2RCYP3A4 | |
| Bromide SCHEMBL1730982 | 0.85 | F2R (0.31) | F2R | |
| Bromide SCHEMBL1729445 | 0.85 | F2R (0.36) | F2RCYP3A4 | |
| Bromide SCHEMBL1731575 | 0.83 | PDE4B (0.35) | PDE4BF2R | |
| Bromide SCHEMBL1728992 | 0.83 | F2R (0.39) | F2RCYP3A4 | |
| Hydrochloric Acid SCHEMBL1730953 | 0.81 | CYP3A4 (0.40) | F2RCYP3A4 | |
| Bromide SCHEMBL1730847 | 0.76 | F2R (0.41) | F2RCYP3A4 | |
| Hydrochloric Acid SCHEMBL1729042 | 0.75 | F2R (0.39) | F2RCYP3A4 | |
| Hydrochloric Acid SCHEMBL1729307 | 0.75 | F2R (0.40) | F2RCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |